Prenatal Exposures Never Die got its start when a mother of two idiopathically (cause unknown) autistic children by chance discovered her own prenatal medical records from 1965, revealing that she had been heavily exposed to a mix of synthetic steroid hormones intended at the time for the prevention of miscarriage. This practice was not uncommon in the 1960s. Having a scientific background and knowing that the fake hormones are potent endocrine disruptors capable of disturbing the process of normal germline development, she suspected that her children's markedly abnormal neurodevelopment stemmed from unforeseen epigenetic perturbations of her eggs.
Several projects are now in the works to determine if part of today's autism epidemic can be traced back to the widespread use of synthetic hormone and other gestational drugs in the second half of the 20th century.
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